If one has to observe the ectopic sites where the pleomorphic adenoma could occur, then of course the regular areas are the pharynx, trachea, larynx, lacrimal glands and the nasal cavity. And the one coming from the nasal septum is one such location where the behavior of the tumor can be studied.
The intranasal one is a rare benign adenoma which grows gradually but has a propensity to recur again post surgical resection. Although the CT scans and the MRI studies are helpful in finding its presence, but the histopathological examinations are of more help.
The symptoms often include the nasal obstruction, a painless mass in the nasal cavity or the epistaxis, but the clinical findings show a firm lobular mass in a structured capsule, where this mass can even bleed on being disturbed. The histological findings for the pleomorphic type reveal both the mesenchymal as well as the epithelial matter.
However, the histopathological findings of the intranasal type has got different features, with cellularity being more in the intranasal tumors making the epithelial cells to predominate in the nasal cavity. And the recurrent adenoma is a myxoid stroma if one goes by the histopathological characteristics. Pathologically, the bigger pleomorphic adenoma of the nasal septum is a multilobular mass, where this can recur again in the nasal cavity.
Looking at the diagnosis of the intranasal pleomorphic adenoma, then it includes tumors of various kinds such as the inverted papilloma, adenocarcinoma, cartilaginous adenoma from the nasal septum, squamous cell carcinoma, etc. The surgical excision with follow-ups with the doctors is the most suggested way to deal with the intranasal pleomorphic adenoma.
